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Faber argued there hasn't been enough change in these federal regulations in the decades following the FDA's approval of titanium dioxide – especially as others increasingly point to potential health consequences.

Lithopone 30% is a perfect alternative to titanium dioxide in all natural and synthetic pigmented elastomers, as it is non-abrasive and extremely acid resistant. 

Ultimately, most experts advise moderation, as titanium dioxide is typically found in processed foods that come with their own health risks.

The whole scientific experimental design in some of these studies is‌ very flawed, Kaminski said.

Lithopone, a white pigment composed of a mixture of barium sulfate and zinc sulfide, is commonly used in the leather industry as a coloring agent. Leather suppliers around the world rely on lithopone to achieve the desired color and finish on their products.

While the conclusions of the EU expert panel were considered in this report, Health Canada's Food Directorate conducted its own comprehensive review of the available science. This included evaluating new scientific data that addressed some of the uncertainties identified by the EU expert panel and were not available at the time of their review.    

Most notably, a European Food Safety Authority safety assessment published in May 2021 pointed to genotoxicity concerns, as suggested by previous research. Genotoxicity is the ability of chemicals to damage genetic information such as DNA, which may lead to cancer.

Titanium Dioxide prices in Germany increased by about 4% in the second quarter compared to what was seen in Q1 from historical price trends. Due to the restrictions on Russian energy imports brought on by the sanctions imposed by European countries, domestic production of TiO2 saw its costs surge even further. Additionally, the commodity's price was highlighted and its market expansion was supported by the upstream construction and automation sectors' buoyant demand.