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Titanium dioxide is used in an enormous range of food products, which can feel jarring when looking at some of its other uses.

That came after a 2021 report from an expert panel at the European Food Safety Authority, which reviewed data on titanium dioxide safety. The panel said it couldn’t rule out concerns that the food additive might be able to damage DNA and possibly lead to cancer. They explained that after you eat something that has titanium dioxide in it, your body absorbs low levels of its particles – but the particles can build up as you eat more foods with this additive.

Titanium dioxide manufacturer: CHTI

Still, you may wonder whether it’s safe for consumption.

In addition to its physical properties, titanium dioxide also has environmental benefits. As a non-toxic compound, it is safe to use in homes, offices and public places. Coatings formulated with titanium dioxide contain virtually no volatile organic compounds (VOCs), ensuring minimal impact on indoor air quality and human health. Additionally, due to their long-lasting nature, titanium dioxide-infused paints can help create a more sustainable environment by reducing waste and the need for frequent repainting.

It adds a bright white color to coffee creamers, baked goods, chewing gums, hard-shell candies, puddings, frostings, dressings, and sauces. But the nanoparticles found in “food-grade” titanium dioxide may accumulate in the body and cause DNA damage—which is one way chemicals cause cancer and other health problems. 

While IARC listed titanium dioxide as “possibly carcinogenic to humans,” they also add that “there is inadequate evidence in humans for the carcinogenicity of titanium dioxide.” Of the four human studies that they reviewed, only one showed a potential risk for occupational workers inhaling titanium dioxide particles and lung cancer, while the other three showed no risk for cancer at all. And it’s key to note that IARC did not assess the effects of titanium dioxide found in foods.

There is some evidence that ingested titanium dioxide does not completely exit the body. A 2015 review of animal studies and a few human studies suggests titanium dioxide can get absorbed into the bloodstream and expose other organs to damage.

Below 10% substitution, 1 kg of TiO2 should be replaced by 1 kg of Lithopone 30%.  

Historically, the first mentions of zinc sulfide being utilized as a pigment were approximately sixty years before the everyday use of lithopone. Originally, it was thought to be appropriate for coloring rubber. In England, a patent was granted for this process. Two decades after this, the focus shifted to zinc sulfide as a suitable pigment for paint. The year 1874 witnessed the patenting of a manufacturing process for a novel white pigment composed of zinc sulfide and barium sulfate. Dubbed Charlton white or Orr’s white enamel, this began a new era for white pigments.