But that depends on how titanium dioxide is being used and how you might come into contact with it. The International Agency for Research on Cancer (IARC) has classified titanium dioxide as possibly carcinogenic to humans based on studies that showed more lung tumors in rats associated with breathing in titanium dioxide.

Titanium dioxide is produced in two main forms. The primary form, comprising over 98 percent of total production, is pigment grade titanium dioxide. The pigmentary form makes use of titanium dioxide’s excellent light-scattering properties in applications that require white opacity and brightness. The other form in which titanium dioxide is produced is as an ultrafine (nanomaterial) product. This form is selected when different properties, such as transparency and maximum ultraviolet light absorption, are required, such as in cosmetic sunscreens.

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Prof Maged Younes, Chair of EFSA’s expert Panel on Food Additives and Flavourings (FAF), said: “Taking into account all available scientific studies and data, the Panel concluded that titanium dioxide can no longer be considered safe as a food additive . A critical element in reaching this conclusion is that we could not exclude genotoxicity concerns after consumption of titanium dioxide particles. After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body”. 

It's also used in sunscreens as a UV filtering ingredient, helping to protect a person's skin by blocking absorption the ultraviolet light that can cause sunburn and cancer.

European food safety regulators have since labeled titanium dioxide as no longer safe for human consumption, due to its potential toxicity. 

When we purchase lithopone, we must pay attention to its ratio. This can be seen to some extent from the appearance. Basically, we can see that good  products are very delicate. , and the color is also very uniform, a kind of shiny white, while inferior lithopone has uneven particles and wrong luster.

Lithopone

Other food products that list titanium dioxide are Lucerne cottage cheese, Beyond Meat's chicken plant-based tenders, Great Value ice cream and Chips Ahoy! cookies.

In addition to Skittles, other candies that contain titanium dioxide include Nice! mints, Trolli sour gummies and Ring Pops, according to Environmental Working Group.