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The design is designed not only for ease of installation, but also for the ability to achieve such installation in harsh terrain conditions such as cliffs, with little anchorage and little excavation for quick and easy installation. Based on the characteristics of heavy hexagonal mesh double stranded structure, even in the case of wire damage can also withstand the impact of falling rock.

Before wall plastering, the wall column is connected to the gap construction wire mesh, which can play a certain strengthening and heat preservation effect. The mesh is hung on the interface surface of different grassroots, and the length of each side should meet the requirements of 100mm, so as to prevent shrinkage and cracking caused by different grassroots. Mesh wire diameter can also determine the effect and efficiency of construction, mesh fine laid up convenient soft, high construction efficiency; Of national standard can assure quality, but laid respect is inferior to fine construction fast.

Hexagonal mesh is also known as twisting mesh, thermal insulation net, soft edge net. Material: low carbon steel wire, stainless steel wire, PVC wire, copper wire knitting: straight twist, reverse twist, two-way twist, first after plating, first plating after knitting, and hot dip galvanized, zinc aluminum alloy, galvanizing, PVC coated, etc. Features: Solid structure, flat surface, with good corrosion resistance, oxidation resistance and other characteristics. Uses: Used for raising chickens, ducks, geese, rabbits and zoo fences, mechanical equipment protection, highway guardrail, etc.

As mentioned above, these oxide NPs are harmful in part because both anatase and rutile forms are semiconductors and produce ROS. Particularly, P25 kind has band-gap energies estimated of 3.2 and 3.0 eV, equivalent to radiation wavelengths of approximately 388 and 414 nm, respectively. Irradiation at these wavelengths or below produces a separation of charge, resulting in a hole in the valence band and a free electron in the conduction band, due to the electron movement from the valence to conduction bands. These hole–electron pairs generate ROS when they interact with H₂O or O₂ [43,44]. It was described that they can cause an increase in ROS levels after exposure to UV-visible light [45]. The NBT assay in the studied samples showed that bare P25TiO₂NPs produce a large amount of ROS, which is drastically reduced by functionalization with vitamin B2 (Fig. 5). This vitamin, also known as riboflavin, was discovered in 1872 as a yellow fluorescent pigment, [46] but its function as an essential vitamin for humans was established more than sixty years later, and its antioxidant capacity was not studied until the end of the XX century [47,48]. This antioxidant role in cells is partially explained because the glutathione reductase enzyme (GR) requires it for good functionality. This enzyme is the one in charge of the conversion of oxidized glutathione to its reduced form which acts as a powerful inner antioxidant and can quench the ROS [49,50]. The cost of this action is that the glutathione is converted to the oxidized form and needs to be recovered by the GR. Consequently, the cells need more vitamin B2. Another glutathione action is the protection against hydroperoxide. This activity is also mediated by riboflavin. Therefore, local delivery of this vitamin seems to significantly help the cells in their fight to keep the oxidative balance, once they are exposed to high levels of ROS.

Nano-sized P25TiO₂NPs were kindly donated by Dr. Scaiano, Ottawa University (Canada). Riboflavin (vitamin B2) was from Sigma and ascorbic acid (vitamin C) and KBr (for IR pills) were from Cicarelli. Base cream for the animal experiments was purchased from Todo Droga and the LED panel was built ad hoc.

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Additionally, the committee noted that the available data did not provide convincing evidence of genotoxicity for titanium dioxide as a food additive, but recognized the limitations in current methodologies with respect to the testing of poorly soluble particulate materials. Although there were uncertainties in the genotoxicity data, the experts took into account the fact that the additive was not carcinogenic in adequately conducted two-year studies in mice and rats at doses of up to 7,500 mg/kg BW per day for mice, and 2,500 mg/kg BW per day for rats, the highest doses tested. There was also no evidence of reproductive or developmental toxicity in studies in rats at doses up to 1,000 mg/kg BW per day, the highest doses tested.