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  • Stability and darkening[edit]

  • Finally, research has shown that titanium dioxide nanoparticles do not pass the first layer of the skin — the stratum corneum — and are not carcinogenic (7Trusted Source15Trusted Source).

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  • In June 2022, Health Canada weighed in on the debate, releasing a report on the safety of titanium dioxide. Their expert panel reviewed toxicity studies, including ones involving genetic damage. The expert panel found that previous studies used different forms and properties of titanium dioxide and deliberately broke the material into smaller particles than what you would normally see in food.

  • ≥105

  • Therefore, today, they only recommend limiting titanium dioxide inhalation in industries with high dust exposure, such as paper production (11).

  • Historical references[edit]

  • Report Overview: