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CSPI says it might reconsider its rating if specifications for food-grade titanium dioxide in the U.S. are updated to ensure nanoparticles are minimized, and new studies are conducted to assess its capacity to cause cancer or other health problems. 

The assessment was conducted following a rigorous methodology and taking into consideration many thousands of studies that have become available since EFSA’s previous assessment in 2016, including new scientific evidence and data on nanoparticles. 

The report provides a detailed location analysis covering insights into the land location, selection criteria, location significance, environmental impact, expenditure, and other lithopone manufacturing plant costs. Additionally, the report provides information related to plant layout and factors influencing the same. Furthermore, other requirements and expenditures related to machinery, raw materials, packaging, transportation, utilities, and human resources have also been covered in the report.

2. What foods contain titanium dioxide?

In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

Lithopone is chemically inert and practically insoluble in acids, alkalis and solvents. The optimized particle-size distribution of Lithopone attained by means of co-precipitation and calcining permit the achievement of a high apparent density, which imparts to Lithopone its low resin requirement and its excellent rheological behaviour.

Those scientists found that sunscreen residue on the roof installers fingertips were being transferred to the colour bond sheets during installation & with titanium dioxide’s photo-sensitivity & the lovely sun’s help, the paint was literally peeling off those roofs.

Applications:

In a review published in 2022 in the journal Archives of Toxicology, researchers found that the ingestion of E171 is a “a definite health risk for consumers and their progeny.” After reviewing dozens of in vivo, ex vivo and in vitro studies on the toxicity of E171, the researchers wrote that two facts must be noted: “First, reprotoxicity studies show that animals of both sexes are impacted by the toxicity of these nanoparticles, underlining the importance of conducting in vivo studies using both male and female animals. Second, human exposure begins in utero via maternal-fetal transfer and continues after birth by breastfeeding. Children are then chronically re-exposed due to their food preferences. To be relevant to the human in vivo situation, experimental studies should therefore consider nanoparticle exposure with respect to the age or life period of the studied population.”

At the same time, the company took the lead in building a product application testing system in the industry, and formed a relatively complete product application testing system. Among them, the hue of blue-phase R838 titanium dioxide reaches the world-class level. The gloss of R838 titanium dioxide, a silicon-aluminum coated product, has surpassed other domestic silicon-aluminum coated products, and reached or even exceeded some domestic zirconium-aluminum products. Titanium dioxide for color masterbatch is recognized by customers for its high whiteness, high coverage and other indicators, the product market share has been greatly increased, and it enjoys high brand awareness and reputation at home and abroad.

Should I be worried about the use of titanium dioxide in my toothpaste?

When it comes to sourcing titanium dioxide, it is essential to understand the various processes involved in its production. The two primary production methods are the sulfate process and the chloride process. The sulfate process tends to be more cost-effective in certain contexts, but it also generates a substantial amount of waste, putting pressure on manufacturers to invest in waste treatment technologies. On the other hand, the chloride process is known for its superior quality and lower environmental impact, albeit at a higher production cost.